Health Condition 1: I252- Old myocardial infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: CABG 40-70 YRS
Exclusion criteria
Exclusion criteria: Emergency Surgeries. Redo-surgeries. Open Sternum Left Ventricular Ejection Fraction Preoperative use of narcotics or illicit drug abuse. History of chronic intractable non-cardiac pain. Liver or Kidney disease Allergy to Amide group of anaesthetics, Morphine or Fentanyl. Arrhythmia history or rhythm disturbances documented in ECG. Haemodynamically unstable patients already on preoperative inotropic support or Intra-arterial balloon pumps (IABP). Anticipated surgery or surgery lasting more than 6hrs. Intubation time more than 12hrs or planned for overnight ventilation. Patients refusing to participate. Patients refusing the offered therapeutic options in either group. Patients refusing for parting with medical data for analysis. Patients refusing to participate after the start of study and desire to leave the study at any point of time. Patients currently enrolled in another study. Patients with inability to provide informed written consent. Inability to complete Pain assessments. Post-operative complications with underlying cardio-respiratory cause requiring return to operative room for re-explorations or reinstitution of mechanical ventilation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality and effectiveness of pain relief will beevaluated for 48 hrs after the surgery with routine in-hospital analgesic protocol using following parameters: 11-point 0-10 Verbal Numeric RatingEffects of the blockade on sedation, ventilation and requirement of concomitant analgesics will be assessed using following methods: a) Alertness of patients in peri-tracheal extubation period, as assessed by Ramsay Sedation score in the initial 48 hours after the block. Timepoint: Quality and effectiveness of pain relief will beevaluated for 48 hrs after the surgery with routine in-hospital analgesic protocol using following parameters: 11-point 0-10 Verbal Numeric RatingEffects of the blockade on sedation, ventilation and requirement of concomitant analgesics will be assessed using following methods: a) Alertness of patients in peri-tracheal extubation period, as assessed by Ramsay Sedation score in the initial 48 hours after the block. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Over-sedation leading to ETCO2 or PaCO2 build up during the ventilator weaning phase or peri-tracheal extubation period 2. Any requirement for temporary discontinuation of opioid infusion. 3. Any postoperative requirement for other supplemental analgesics Timepoint: 4 HRLY | — |
Countries
India
Contacts
SCTIMST