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Comparing the efficacy of ketamine and paracetamol in reducing pain due to propofol injection during induction of general anaesthesia

An Observational study comparing the efficacy of low dose ketamine and paracetamol pretreatment in alleviating pain due to propofol injection.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/09/021299
Enrollment
300
Registered
2019-09-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: IV KETAMINE 0.2mg/kg prior to propofol injection: IV PARACETAMOL 2 mg/kg prior to propofol injection

Sponsors

DRSHAJI MATHEW
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status (ASAPS) I and II patients undergoing elective surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: Suspected allergy to propofol,ASAPS 3 and 4,patient refusal,emergency surgeries

Design outcomes

Primary

MeasureTime frame
to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 minTimepoint: to observe for pain reduction immediately after administration of 1/3rd dose of propofol then 1 min and 2 min—

Secondary

MeasureTime frame
to observe for hemodynamic changes if any before administering drug ,after intubation ,5 mins after intubation ,10 mins after intubationTimepoint: 0,5,10 mins—

Countries

India

Contacts

Public ContactDRSHAJI MATHEW

KASTURBA MEDICAL COLLEGE

shajimanipal@yahoo.co.in6360834412

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026