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Changes in prefrontal cortex in schizophrenia

Prefrontal Cortex Gyrification, Cortical thickness,Grey Matter volume and executive functions in Patients with Schizophrenia- A comparative study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/09/021265
Enrollment
45
Registered
2019-09-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F20- Schizophrenia

Interventions

None listed

Sponsors

Central Institute of psychiatry
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. First episode schizophrenia duration of illness 6 month or less. 2.Chronic Schizophrenia illness more than 2 year. 3.No comorbid psychiatric illness or substance dependence 4. Educated upto 8 class 5.Giving written consent

Exclusion criteria

Exclusion criteria: 1.Current neurological or comorbid psychiatric disorder 2. History of substantial brain damage or any neurological procedures. 3. Metallic implants. 4.Score of more than 3 on general health questionnaire-12 5. Not giving written informed consent.

Design outcomes

Primary

MeasureTime frame
Difference between gyrification,cortical thickness,Grey Matter volume in first episode schizophrenia, chronic schizophrenia and healthy controls.Timepoint: Will be assessed within 1 week—

Secondary

MeasureTime frame
Difference in executive functions of first episode schizophrenia and chronic schizophreniaTimepoint: Patients will be assessed in 1 week for executive functions—

Countries

India

Contacts

Public ContactDr Surendra Paliwal

Central Institute of psychiatry

itsme.paliwal@gmail.com8005940887

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026