Role of a diet(neutropenic diet) in reducing infections in children on chemotherapeutic drugs for cancer

Neutropenic Diet vs Standard Indian diet in reducing the incidence of febrile neutropenia following chemotherapy in pediatric oncology patients: A Randomised controlled Trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/09/021252

Enrollment

Registered

2019-09-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-D49- Neoplasms

Interventions

Intervention1: Neutropenic Diet: A specific diet restricting intake of certain food items like uncut vegetables, fruits, unboiled eggs , unpasteurised milk, uncooked nuts/dry fruits Duration - 1 month

Eligibility

Inclusion criteria

Inclusion criteria: 1. Paediatric oncology patients aged 3-14 years receiving strongly myelosuppressive chemotherapy 2. Taking more than 50 % caloric intake per orally at time of inclusion in the study

Exclusion criteria

Exclusion criteria: 1.Patients unwilling to give consent 2. Patients receiving myeloablative chemotherapy in preparation for allogeneic or autologous bone marrow or stem cell transplant. 3. Co-morbidity with immunosuppressive disease such as AIDS. 4. Patients with documented infection at time of enrolment. 5. Patients who are not fed orally (G-tube dependant, TPN-dependant) at time of enrolment 6. Patients actively receiving radiation

Design outcomes

Primary

Measure	Time frame
To determine the incidence of febrile neutropenia (following chemotherapy) in paediatric oncology patients receiving Neutropenic diet versus patients receiving standard Indian dietTimepoint: One Chemotherapeutic cycle(around 1 month)	—

Secondary

Measure	Time frame
To determine the adherence of each arm to their respective dietsTimepoint: One Chemotherapeutic cycle(around 1 month);To determine the incidence of common infection in both the armsTimepoint: One Chemotherapeutic cycle (Around One Month);To determine the length of antibiotic usage in both armsTimepoint: One Chemotherapeutic cycle(around 1 month)	—

Countries

India

Contacts

Public ContactAditya Gupta

All India Institute of Medical Sciences, New Delhi

adivick@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026