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Alternative to root canal treatment in teeth with open root ends - a comparison of two techniques

A comparison of two pulp revascularization techniques using platelet rich plasma and whole blood clot

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/09/021209
Enrollment
40
Registered
2019-09-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: Using whole blood in the root canal for revascularisation: Whole blood obtained by deliberate overinstrumentation of the root canal will be used as a scaffold inside the root canal, on

Sponsors

Department of Conservative Dentistry and Endodontics
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with immature permanent teeth with necrotic pulps and/or apical periodontitis.

Exclusion criteria

Exclusion criteria: Patients with a significant medical history such as bleeding disorders and those with teeth having a poor periodontal and restorative prognoses were excluded from the study. Patients with known allergies to antimicrobial drugs were also excluded from the study.

Design outcomes

Primary

MeasureTime frame
Resolution of periapical radiolucency on radiograph, and resolution of symptonsTimepoint: 6 months (March 2020) and 12 months (September 2020)—

Secondary

MeasureTime frame
Increase in root length and root width as measured radiographicallyTimepoint: 6 months and 1 year—

Countries

India

Contacts

Public ContactNaren Ramachandran

Terna Dental College & Hospital

narenr89@gmail.com9821156834

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026