A â??study to see the effect of screening â??for mouth and food pipe cancer using visual â?? examination and x ray

Effect of screening with visual examination and double contrast barium swallow on oral and upper aerodigestive tract cancer mortality- a cluster randomized trial.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/09/021178

Enrollment

110000

Registered

2019-09-11

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Screening with health education: Subjects will be screened routinely for cancer in addition of health education and counselling on cessation of tobacco and alcohol use. Further treatmen

Eligibility

Inclusion criteria

Inclusion criteria: Individuals at high risk of esophageal and hypopharyngeal cancers-chronic tobacco users(cumulative use more than 5 years) (or) betel nut and areca nut chewers (or) alcohol use (cumulative use more than 5 years)

Exclusion criteria

Exclusion criteria: 1. People with low performance status ( ECOG score > 2) 2. Patients with pre existing symptoms of esophageal and hypopharyngeal cancers (persistent dysphagia, odynophagia and/or haorseness

Design outcomes

Primary

Measure	Time frame
Reduction in esophageal and hypopharyngeal cancer related- mortality and oral cancer related mortality.Timepoint: Five years after completion of screening	—

Secondary

Measure	Time frame
1. Improvement in survival after diagnosis of esophageal and hypopharyngeal cancers. 2. Diagnostic sensitivity and specificity of double contrast barium swallow in diagnosis of asymptomatic esophageal and hypopharyngeal cancers. 3. Cost effectiveness of screening for esophageal and hypopharyngeal cancers in community. 4. Assess possible aetiological factors associated with causation of esophageal and hypopharyngeal cancers.Timepoint: Five years after completion of screening	—

Measure

Time frame

1. Improvement in survival after diagnosis of esophageal and hypopharyngeal cancers. 2. Diagnostic sensitivity and specificity of double contrast barium swallow in diagnosis of asymptomatic esophageal and hypopharyngeal cancers. 3. Cost effectiveness of screening for esophageal and hypopharyngeal cancers in community. 4. Assess possible aetiological factors associated with causation of esophageal and hypopharyngeal cancers.Timepoint: Five years after completion of screening

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Countries

India

Contacts

Public ContactDr CS Pramesh

Tata Memorial Hospital

prameshcs@tmc.gov.in022-24177070

Outcome results