"SAFETY AND EFFICACY OF ORAL AND VAGINAL MISOPROSTOL FOR INDUCTION OF LABOUR IN TERM PREGNANCIESâ??- A RANDOMISED CONTROLLED TRIAL IN A TERTIARY HEALTH CENTRE

"SAFETY AND EFFICACY OF ORAL V/S VAGINALLY ADMINISTERED MISOPROSTOL FOR INDUCTION OF LABOUR IN TERM PREGNANCIES- A RANDOMISED CONTROLLED TRIAL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/09/021130

Enrollment

154

Registered

2019-09-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O481- Prolonged pregnancy

Interventions

Intervention1: ORAL MISOPROSTOL: 25mcg Q2h x total 5 doses for 1 day SAFETY AND EFFICACY OF ORAL AND VAGINALLY ADMINISTERED MISOPROSTOL FOR INDUCTION OF LABOUR IN TERM PREGNANCIES Control Intervention

Eligibility

Inclusion criteria

Inclusion criteria: Nulliparous and Multiparous women at term(37-42 completed weeks of gestation with first trimester ultrasound confirmed dates),with a singleton fetus of Cephalic presentation with : Clinically adequate pelvis Reassuring fetal heart tracing, ,Modified bishopâ??s score of less than 6 [1]Gestational diabetes mellitus, [2] gestational hypertension, [3]past date, [4]oligohydramnios, [5]Premature rupture of membranes[ Are eligible for this trial

Exclusion criteria

Exclusion criteria: All patients with [1]severe systemic illnesses like uncontrolled diabetes mellitus, severe pre-eclampsia, cardiac, renal or hepatic disease, [2] IUGR, [3]intrauterine deaths [4]hypersensitivity to misoprostol or any prostaglandin analogue [5] Patients with any contraindication to induction and vaginal delivery, e.g. cephalopelvic disproportion, malpresentation, fetal compromise, non reassuring fetal heart rate pattern, previous scar and ante partum haemorrhage. [6] Patients who are not willing to participate in this study

Design outcomes

Primary

Measure	Time frame
Outcome variables. - Primary Caesarean for fetal distress,Timepoint: 1 year	—

Secondary

Measure	Time frame
Induction delivery interval Maternal and perinatal outcomeTimepoint: 2weeks	—

Countries

India

Contacts

Public ContactDRRESHMA RAJENDRAN

MOSC MEDICAL COLLEGE

aniesoman@gmail.com9995782050

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026