To evaluate the efficacy of Dexmedetomidine with Ketamine for awake fiberoptic intubation

A Comparative study between dexmedetomidine plus ketamine and propofol plus ketamine for fiberoptic intubation in adult patients with simulated cervical spine injury

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/09/021111

Enrollment

Registered

2019-09-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H619- Disorder of external ear, unspecified

Interventions

Intervention1: Fiberoptic intubation: Awake fiberoptic intubation with simulated cervical injury Control Intervention1: Dexmedetomidine and propofol: 0.5 mcg/kg/h, 0.5 mg kg -1

Eligibility

Inclusion criteria

Inclusion criteria: ASAI and II

Exclusion criteria

Exclusion criteria: 1. Patients having major cardiac, neurological, hepatic, renal, pulmonary illness or coagulation abnormalities. 2. Patients having any anatomical abnormality of upper airway like DNS, tumours, foreign body, polyp etc. on ENT Examination. 3. Patients having history of hypersensitivity reactions to any of the drugs under study.

Design outcomes

Primary

Measure	Time frame
Intubation ScoresTimepoint: After insertion of fiberoptic scope to visualization of vocal cords	—

Secondary

Measure	Time frame
Intubation time, side effects , hemodynemic stability, patient satisfactionTimepoint: Intubation time-time from insertion of fiberoptic scope to confirm placement of endotracheal tube. Side effects- intra and postoperative complications within 24 hours, Hemodynamic parameters- Baseline 0 minutes, 2 minutes, 3, 4, 5 , 6 minutes patient satisfaction- postoperative period	—

Countries

India

Contacts

Public ContactNeelam Sharma

LLRM Medical College Meerut UP

drvipindhama@Yahoo.com9760014177

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026