Comparison of efficacy between magnesium sulphate and dexamethasone when used in interscalene block for postoperative pain relief in patients undergoing shoulder repair surgery.

A Comparative study between magnesium sulphate and bupivacaine versus dexamethasone and bupivacaine in ultrasound-guided interscalene brachial plexus block for postoperative analgesia in patients undergoing shoulder arthroscopic repair under general anaesthesia. A prospective interventional randomized comparative double blind study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/09/021099

Enrollment

Registered

2019-09-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S460- Injury of muscle(s) and tendon(s)of the rotator cuff of shoulder

Interventions

Intervention1: Magnesium sulphate,Bupivacaine: 250mg(1ml),0.25%(24ml) Total 25 ml drug used in ultrasound guided Interscalene brachial plexus block in patients under general anaesthesia intraoperativ

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 18-70 years 2. ASA grade I to II 3. Willing and able to give consent 4. Patients undergoing elective shoulder arthroscopic repair surgeries

Exclusion criteria

Exclusion criteria: 1. ASA > II . 2. Diabetics with neuropathies, presence of other neuropathies involving brachial plexus. 3. Uncontrolled hypertension. 4. Morbidly obese patients/ BMI > 40. 5. Patient refuse to give informed consent. 6. Known Allergy to any drug used in the study. 7. Inability to give regional block due to local site problem for example infection. 8. Drug dependence. 9. Patients on anticoagulants. 10. Long standing cardiac, hepatic and renal disease. 11. Chronic treatment with calcium channel blockers. 12. Patients with raised serum magnesium levels. 13. Inability to communicate with investigator or hospital staff.

Design outcomes

Primary

Measure	Time frame
Post operative analgesiaTimepoint: 24 hours	—

Secondary

Measure	Time frame
Dose of rescue analgesia required, Duration of motor block,Fentanyl requirement,adverse effectsTimepoint: 4th hourly for 24 hours post operatively	—

Countries

India

Contacts

Public ContactDr Jaswinder

Fortis Hospital Mohali

drrajput2011@gmail.com8054814999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026