comparing the effect of preloaded alkalanized lignocaine cuff vs alkalanized lignocaine cuff loaded after intubation to reduce of cough after a brief surgery

To compare the efficacy of preloaded alkalanized lignocaine cuff vs conventional alkalanized lignocaine cuff to reduce emergence cough after a brief surgery : a prospective randomized controlled study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/09/021097

Enrollment

Registered

2019-09-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N211- Calculus in urethra

Interventions

Intervention1: preloaded alkalanized lignocaine cuff: the cuff of endotracheal tube will be filled with 10 ml of alkalanized lignocaine cuff 90 minutes prior to surgery Control Intervention1: conventi

Eligibility

Inclusion criteria

Inclusion criteria: any surgeries that requires general anaesthesia and lasting for less than 2 hours.

Exclusion criteria

Exclusion criteria: asthmatic any respiratory tract disease anticipated difficult airway allergies to local anaesthesia

Design outcomes

Primary

Measure	Time frame
presence of cough at the time of extubation(removal of endotracheal tube )Timepoint: measured at the time just before removal of endotracheal tube and 5 minutes after tube removal , then 1hr 2nd hr 4th hr 6th hr 12th hr 24th hr post surgery .	—

Secondary

Measure	Time frame
sore throat cough hoarseness of voiceTimepoint: at extubation 1hr after extubation	—

Countries

India

Contacts

Public Contactritika swaminathan

sri ramachandra institute of higher education and research

thames25@gmail.com9841552333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026