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Effect of hypertonic saline on fluid requirement during major abdominal surgery.

Influence of 3% hypertonic saline on intraoperative maintenance fluid requirement in patients undergoing major abdominal surgery in comparison with 0.9% normal saline.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/09/021032
Enrollment
100
Registered
2019-09-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: 3% Hypertonic saline: 3% Hypertonic saline will be infused through a wide bore cannula @ 1ml/kg/hr Control Intervention1: 0.9% Normal saline: 0.9% Normal saline will be infused with a w

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of ASA1 and ASA2 2. Surgeries lasting more than 2 hours 3. Expected hospital stay of more than 3 days

Exclusion criteria

Exclusion criteria: 1. Patients refusal to give consent 2. Inoperability 3. Emergency 4. Disturbances in serum sodium levels 5. Baseline elevated serum creatinine 6. Laproscopy

Design outcomes

Primary

MeasureTime frame
Difference in intraoperative maintenance fluid requirementsTimepoint: Intraoperative—

Secondary

MeasureTime frame
1.Difference in 24hr fluid requirement 2. Need of vasopressors in 24hrs 3. Difference in arterial lactate level at 12 and 24 hrs 4. Difference in 24 and 48 hr serum creatinine 5.24hr CRPTimepoint: 72 hours post operatively—

Countries

India

Contacts

Public ContactDr Satyajeet Misra

All India Institute of Medical Sciences,Bhubaneshwar

misrasatyajeet@gmail.com9438884048

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 13, 2026