Health Condition 1: E106- Type 1 diabetes mellitus with other specified complications Health Condition 2: E116- Type 2 diabetes mellitus with other specified complications
Conditions
Interventions
None listed
Sponsors
Manipal Center for Infectious Diseases
Eligibility
Inclusion criteria
Inclusion criteria: 1. Both genders 2. Age 18 years or older 3. Patients with type 1 or 2 DM 4. Newly diagnosed foot ulcers 5. IDSA: uninfected. (For DFU patients) 6. IDSA: mild/moderate (For DFI patients) 7. Volunteers without a previous history of DM who has come for regular health check-up or blood donation (healthy controls) 8. Participants willing to give the informed consent form and participate in the study
Exclusion criteria
Exclusion criteria: 1. Individuals with hepatic disease, renal disease, or other comorbidities that can alter vitamin D levels 2. Diagnosis of lower limb critical ischemia by Doppler ultrasound and ankle/arm index less than 0.5 3. Patients with lower limb ulcers with distal necrosis 4. Patients having clinical evidence of vascular insuf�ciency 5. Patients currently on steroid (use in the past 30 days) cytotoxic drugs, immunosuppressants, Calcium supplements, multivitamins, and drugs that could alter vitamin D status 6. Pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Wound Healing Health Related Quality of Life (HRQoL)Timepoint: 4 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of lifeTimepoint: 4 months | — |
Countries
India
Contacts
Public ContactShilia Jacob Kurian
Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences
Outcome results
None listed