Health Condition 1: D498- Neoplasm of unspecified behavior of other specified sites
Conditions
Interventions
Control Intervention1: Malnourished Patients: Proteomic and metabolomic profiles of malnourished patients
Control Intervention2: Well nourished Patients: Proteomic and metabolomic profiles of well nou
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Histologically or cytologically confirmed Diagnosis of a solid tumour Aged 1-10 years Patient should be treatment naïve. Patients in whom chemotherapy is indicated
Exclusion criteria
Exclusion criteria: Patients who are on nutritional supplements before first blood collection Patients with active infection, uncontrolled diabetes, receiving glucocorticoid therapy, or having esophageal-gastrointestinal obstructions responsible for feeding limitations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate the differences in metabolomic and proteomic markers in peripheral blood of cancer patients belonging to different nutritional statusTimepoint: The study will be conducted at two time-points : Time point 1 is at at diagnosis , and Time point 2 is 3 months from diagnosis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Validate the animal model of malnutrition being developed in our lab by comparing its proteome and metabolome against the profiles observed in malnourished cancer patients Change in the proteomic and metabolomics profile of cancer patients belonging to different nutritional groups over a period of timeTimepoint: The study will be conducted at two time-points : Time point 1 is at diagnosis , and Time point 2 is 3 months from diagnosis. | — |
Countries
India
Contacts
Public ContactMegha Garg
Tata Memorial Hospital
Outcome results
None listed