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Role of Magnesium Sulphate drug in reducing muscle contraction during general anesthesia induction after giving succinylcholine and in reducing post op pain.

Efficacy Of Magnesium Sulphate In Attenuating Succinylcholine Induced Fasciculation And Post Operative Myalgia: An Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/09/021014
Enrollment
70
Registered
2019-09-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: NIL: NIL Control Intervention1: GROUP M: IN THIS GROUP PATIENTS RECEIVE MAGNESIUM SULPHATE 35 MG PER KILOGRAM BODY WEIGHT BEFORE INDUCTION AFTER DILUTION UPTO 10 ML WITH DISTILLED WATER

Sponsors

Department of Anesthesiology and Critical Care
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient with ASA grade 1 and 2 and of age group 18 to 60 years of either sex undergoing elective surgeries under general anaesthesia and willing to give a written and informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients not willing to be a part of this study. 2. Patients who are having known allergy to the study drugs. 3. SBP 4. Patients with history of myasthenia gravis, muscular dystrophy or any other neuromuscular disease. 5. Patients with history of epilepsy/seizure disorder. 6. Patients who are taking antihypertensive medications (hypertensive patient). 7. Pregnant patients. 8. Raised intracranial pressure, raised intraocular pressure, hypotension history, diabetics, neurological patients, burn patient, hyperkalemia patient, history of gastric reflux. 9. Patients taking analgesics.

Design outcomes

Primary

MeasureTime frame
Fasciculations will be seen just after succinylcholine injection and graded as:- 1. Nil (absent) 2. Mild (fine fasciculations of eyes, face , neck or fingers without movement of limbs) 3. Moderate (obvious muscle twitching at more than one sites or movement of limbs) 4. Severe (vigourous, sustained and widespread fasciculations) Timepoint: Fasciculations will be seen just after giving succinylcholine injection—

Secondary

MeasureTime frame
Postoperative myalgia seen after 24 hours of surgery and graded as:- Grading 1. Nil (absence of pain) 2. Mild (muscle stiffness or pain on specific questioning in nape of neck, shoulders and lower chest on deep breathing) 3. Moderate (muscle stiffness and pain complained of by the patient spontaneously requesting analgesia) 4. Severe ( generalized muscle stiffness or pain which limits physical activity) 5. Worst possible pain Timepoint: after 24 hours of surgery—

Countries

India

Contacts

Public ContactDR F S BHATI

DR S N MedicalL College, Jodhpur

fatehbhati@yahoo.co.in9414127176

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026