FindTrial
Sign In

Infusion of drugs to prevent fall in blood pressure after spinal anesthesia during caesarean delivery

Comparison of continuous Norepinephrine versus Phenylephrine infusion in prevention of hypotension after spinal anesthesia during caesarean delivery -a Prospective randomized study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020995
Enrollment
208
Registered
2019-08-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: norepinephrine: Dose:0.05mics/kg/min
infusion will be started at the same time cerebrospinal fluid obtained,infusion continued till end of the procedure. Control Intervention1: phenylephrine: started at a dose of 0.1mics/kg/min
drug infusion will be started at the same time cerebrospinal fluid obtained
infusion continued till the end of the procedure.

Sponsors

Sri Ramachandra institute of higher education and research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA II,III Singleton gestation more than 36 weeks Scheduled elective caesarean delivery under spinal anesthesia Fasting more than six hours

Exclusion criteria

Exclusion criteria: ASA IV or above,Emergency Surgeries

Design outcomes

Primary

MeasureTime frame
Reduction in number and total dose of intraoperative provider administered rescue bolus of phenylephrine needed to maintain systolic blood pressure (SBP).Timepoint: bolus of phenylephrine and ephedrine given whenever there is a reduction in blood pressure of 20% from baseline—

Secondary

MeasureTime frame
Neonatal Outcome including ï?? Umbilical venous blood gases - pH - pCO2 (mm hg) - pO2 - HCO3 ï?? APGAR scores at 1minute and 5minutes Timepoint: blood sample taken from umblical cord before placental seperation—

Countries

India

Contacts

Public ContactARTHI K

Sri Ramachandra institute of higher education and research

reetharun@gmail.com9942264888

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026