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Effect of immunonutrient therapy on health status among liver disease patients waiting for liver transplantation- A Randomized Controlled Trial

Effect of Immunonutrition on nutritional status and inflammatory markers among end stage liver disease patients waiting for liver transplantation- A randomised controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020973
Enrollment
144
Registered
2019-08-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K746- Other and unspecified cirrhosis ofliver

Interventions

Intervention1: Immunonutrition effects on nutritional status and inflammatory markers: Patients will be recruited based on eligibility criteria from Surgical Gastroenterology Department, JIPMER. After

Sponsors

Jawaharlal Institute of postgraduate Medical Education Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) Listed for first liver transplantation

Exclusion criteria

Exclusion criteria: a)History of hypersensitivity to immunonutrients b)Inability to take oral nutrition c)Patients with fulminant or sub acute hepatic failure/ critically ill patients d)Pregnant or nursing women

Design outcomes

Primary

MeasureTime frame
To assess the effect of immunonutrition on nutritional status, pro- inflammatory markers, anti inflammatory marker and biochemical parameters among ESLD patients waiting for Liver transplantation and expected to reduce the inflammatory markers especially IL6.Timepoint: outcome will be assessed at the time of enrolment as baseline and after one month of immunonutrient therapy and planning to do interim analysis after one-third of enrolment of total sample size is over.till now enrolment of patients is not yet one-third due to covid issues.

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactSafeena BeeviSS

JIPMER

safeenasamadu@gmail.com7598729091

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026