Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: K36- Other appendicitis
Conditions
Interventions
Intervention1: Clonidine: Dose -150 micrograms
Frequency - only once via intrathecal route prior to general anaesthesia
Duration - duration as short as possible to administer the drug via intrathecal
Sponsors
Bangalore Medical College and Research Institute
Dr Surekha C
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients willing to give informed written consent. 2) ASA physical status I and II patients. 3) Patients of age group 18-55 years, of either sex. 4) Patients undergoing elective laparoscopic surgeries under general anaesthesia lasting less than 2 hours. 5) Patients with Body Mass Index between 18 to 30 kilograms per metre square.
Exclusion criteria
Exclusion criteria: 1) Patients with contraindications to spinal technique. 2) Patients with known allergy to clonidine and fentanyl. 3) Patients with cardiovascular and respiratory diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Haemodynamic variablesTimepoint: Intraoperative period - every five minutes till 30 minutes followed by every ten minutes till 60 minutes followed by every fifteen minutes till the end of the surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| AnalgesiaTimepoint: The time required for the patient in the post operative ward for the first rescue analgesic when Visual analogue score is greater than 3;Haemodynamic response to intubation and extubationTimepoint: After one minute and five minutes of intubation and after one minute and five minutes of extubation;Incidence of hypotension, hypertension, bradycardia, tachycardiaTimepoint: 24 hours in the post operative period;SedationTimepoint: Five minutes immediately after extubation in the post operative period | — |
Countries
India
Contacts
Public ContactDr Surekha C
Bangalore Medical College and Research Institute
Outcome results
None listed