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Nebulization before giving anaesthesia to reduce the post surgery pain in throat.

Effect of Nebulization with dexmedetomidine on post-operative sore throat: A prospective randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020907
Enrollment
80
Registered
2019-08-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: nebulization (inhalational) with 0.5micrograms/kg (3ml volume), dexmedetomidine for 15 mins: patients undergoing laparoscopic cholecystectomy would be nebulized with dexmedetomidine pre

Sponsors

Post Graduate Institute of Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status I and II patients who are scheduled for elective laparoscopic surgery under general anaesthesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: Exclusion criteria will include patients with pre-operative sore throat, asthma, known case of chronic obstructive pulmonary disease, oral or head and neck surgery, recent non-steroidal anti-inflammatory drug therapy and mallampati grade >2 and more than 2 attempts of intubation.

Design outcomes

Primary

MeasureTime frame
Incidence of POST 4hours after extubationTimepoint: Incidence of POST 4hours after extubation

Secondary

MeasureTime frame
Incidence of POST immediately after extubation and post operatively (0,2,8,12,24 hrs), severity of POST post operatively (0,2,4,8,12,24hrs). Post-operative nausea vomiting, coughing episodes till 15 minutes after extubation, side effects bradycardia, hypotension and respiratory depression.Timepoint: 0,2,4,8,12,24hrs post operatively

Countries

India

Contacts

Public ContactAnudeep Jafra

Post Graduate Institute of Medical Education and Research

anu_gmch@yahoo.co.in919888027699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026