Health Condition 1: G710- Muscular dystrophy
Conditions
Interventions
Intervention1: pañca cūta meḻuku: Dose: 1mg/kg with sufficient quantity of honey
Duration: The drug will be administered for a period of 10 cycles, in which 1 cycle involves bi-dose administration
Sponsors
Geetha Sudheer R
Eligibility
Inclusion criteria
Inclusion criteria: Subject should be positive for at least two of the criteria given below 1. Elevated CPK levels 2. Genetic testing: Pathogenic deletion, duplication or point mutation of muscular dystrophy related genes 3. Gait abnormality: waddling, wide-based gait with hyperlordosis of the lumbar spine and toe walking 4. Positive Gowerâ??s sign 5. Phenotypic evidence of muscular dystrophy Willing for functional assessment and ability to comply with scheduled visits, and study restrictions.
Exclusion criteria
Exclusion criteria: Children with Heart failure Continuous mechanical ventilation Under continuous usage of other medications Renal insufficiency, retinal disorder, Hypotension or Hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean change in - 6Minute Walk Test - CPK levels - North Star Ambulatory AssessmentTimepoint: 45 days, 90 days, 135 days, 180 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardia and Pulmonary function test Liver and Renal function testsTimepoint: 45 days, 90 days, 135 days and 180 days | — |
Countries
India
Contacts
Public ContactGeetha Sudheer R
Government Siddha Medical College and Hospital
Outcome results
None listed