Health Condition 1: O85- Puerperal sepsis
Conditions
Interventions
Intervention1: Injection cefazolin: Cephalosporin given preoperatively 30 minutes before cesarean section
Control Intervention1: Injection ceftriaxone: cephalosporin given preoperatively as well as po
Sponsors
Dr Krishna Agarwal
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women with term pregnancy (37 to 41 completed weeks) undergoing elective or emergency cesarean section
Exclusion criteria
Exclusion criteria: 1. Women with clinical evidence of infection- fever or leucocytosis 2. Women already receiving or scheduled to receive antibiotic therapy for some other reason 3. Moderate anemia (hb at enrolment) 4. Known HIV positivity 5. Women with heart disease needing antibiotic prophylaxis from prevention of SABE 6. Second stage caesarean section 7. Rupture of membranes ( >24hours) 8. Women with penicillin allergy 9. BMI > 30 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical site infection (SSI) according to CDC criteriaâ?? a. Superficial surgical site infection b. Deep surgical site infection c. Endometritis Endometritis would be identified by uterine tenderness, foul smelling lochia and fever â?¥100.40CTimepoint: 30 days postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Womanâ??s duration of hospital stay 2. Babyâ??s NICU/nursery stay i/v/o infection 3. Readmission for surgical wound infection 4. Side-effects related to antibiotics- Diarrhoea/vomiting/metallic taste 5. Extravasation and thrombophlebitisTimepoint: 30 days of cesarean | — |
Countries
India
Contacts
Public ContactHansveen Kaur Lamba
Lok Nayak Hospital, Delhi
Outcome results
None listed