Health Condition 1: - Health Condition 2: C71- Malignant neoplasm of brain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex Patients aged 18 to 65 years American Society of Anesthesiologists physical status grade I and II Patients scheduled for elective neurosurgical procedures under general anesthesia with tracheal intubation
Exclusion criteria
Exclusion criteria: Patients with uncontrolled hypertension Patients with preoperative bradycardia, ischemic heart disease, cardiac arrhythmias Patients with severe hepatic and renal disease Patients with past history of craniotomy Patients allergic to study drugs Patients on alpha blockers treatment preoperatively Patient refusal Patient unable to give consent Pregnant women and lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate , systolic blood pressure , diastolic blood pressure and mean arterial pressure are measured at different time points following skull pin placement .Timepoint: Heart rate , systolic blood pressure , diastolic blood pressure and mean arterial pressure are measured at 1 3 5 10 minutes following skull pin placement | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. Number of episodes of hypertension, hypotension, bradycardia and tachycardiaTimepoint: during study period. | — |
Countries
India
Contacts
Sri Venkateshwara Institute Of Medical Science