Comparison of modes of ventilation in spine surgery in prone position.

Comparison of pressure control ventilation with volume control ventilation in patients undergoing spine surgery in prone position.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/08/020811

Enrollment

Registered

2019-08-21

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D334- Benign neoplasm of spinal cord Health Condition 2: S320- Fracture of lumbar vertebra Health Condition 3: S220- Fracture of thoracic vertebra Health Condition 4: C720- Malignant neoplasm of spinal cord Health Condition 5: S331- Subluxation and dislocation of lumbar vertebra

Interventions

Intervention1: NIL: NIL Intervention2: Pressure control ventilation: PFT will be performed using spirometer and FVC, FEV1 and PEFR will be noted preoperatively. In the operative room, all routine vita

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients aged 18 to 60 years, of either sex, belonging to ASA physical status I â?? II scheduled to undergo thoracolumbar spine surgery (for tumors or trauma) in prone position under general anesthesia will be enrolled in the study.

Exclusion criteria

Exclusion criteria: Patients having Bronchopulmonary disease (like asthma, chronic bronchitis, emphysema), Cardiac disease, BMI >30 kg/m2, Cerebrovascular disease, Neuromuscular disorder and Multiple trauma will be excluded from the study.

Design outcomes

Primary

Measure	Time frame
1. Respiratory mechanics (peak airway pressure, plateau pressure, lung compliance, dead space and oxygenation). 2. Pulmonary function tests (Vital capacity, Peak expiratory flow rate, forced expiratory volume in first second).Timepoint: Respiratory mechanics will be assessed for both pressure control and volume control ventilation intraoperatively. PFTs will be done preoperatively the same day as baseline, intraoperatively and one day postoperatively only. The above data will be compiled and appropriate statistical test will be used to analyse the results.	—

Measure

Time frame

1. Respiratory mechanics (peak airway pressure, plateau pressure, lung compliance, dead space and oxygenation). 2. Pulmonary function tests (Vital capacity, Peak expiratory flow rate, forced expiratory volume in first second).Timepoint: Respiratory mechanics will be assessed for both pressure control and volume control ventilation intraoperatively. PFTs will be done preoperatively the same day as baseline, intraoperatively and one day postoperatively only. The above data will be compiled and appropriate statistical test will be used to analyse the results.

—

Secondary

Measure	Time frame
Haemodynamic parameters (Heart rate, blood pressure, SpO2)Timepoint: The above outcome will be assessed for both pressure control and volume control ventilation intraoperatively only. Data will be compiled and appropriate statistical test will be used to analyse the results.	—

Countries

India

Contacts

Public ContactDr Poonam Godhwal

Pt. B.D. Sharma PGIMS Rohtak (Haryana)

godhwalpoonam@yahoo.in9968646162

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026