this is a comparision of different proportions of Propofol-Ketamine combination in the ratios 2:1 and 4:1 as infusion for Total Intravenous Anaesthesia in Short Gynaecological Procedures.

A Comparative study of different proportions of Propofol- Ketamine combination for Total Intravenous Anaesthesia in Short Gynaecological Procedures

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/08/020808

Enrollment

146

Registered

2019-08-21

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N979- Female infertility, unspecified Health Condition 2: N839- Noninflammatory disorder of ovary,fallopian tube and broad ligament, unspecified

Interventions

Intervention1: Propofol - Ketamine mixture: Propofol is a rapid,short acting, smooth inducing agent. Ketamine is has analgesic property and causes amnesia A mixture of these drugs in the ratios 2:1

Eligibility

Inclusion criteria

Inclusion criteria: 1. American society of Ananesthesiologists physical status I and II 2. Approximate duration of surgey lasting for less than or equal to 30 mins

Exclusion criteria

Exclusion criteria: 1.American society of Ananesthesiologists physical status III and IV 2.History of allergic reactions to drugs used in the study. 3.Patients with psychiatric illness

Design outcomes

Primary

Measure	Time frame
Onset and duration of action of study drug mixture. Timepoint: DURATION FOR ONSET OF ACTION is taken from the start of administration of drug till the abolition of eyelash reflex	—

Secondary

Measure	Time frame
time for recovery post operative complicationsTimepoint: TIME FOR RECOVERY : to shift the patient from OR to Post anesthetic care unit (taken from the end of infusion till the patient responds to verbal commands) POSTOPERATIVE NAUSEA AND VOMITING : (for a period of 2 hrs. rescue drugs any if given)	—

Countries

India

Contacts

Public ContactDr Pradip Kumar Maharana

Kalinga Institute of Medical Sciences

dr.pradip.maharana@gmail.com8895440004

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026