Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified Health Condition 2: K769- Liver disease, unspecified
Conditions
Interventions
Sponsors
Institute of Liver and Biliary Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosed cases of NASH with Cirrhosis. 2. Age >= 8 year 3. All the first degree relatives of NRC i.e index case. 4. Subject with no history of any known liver disease 5. Non-Alcoholic 6. Matched with age (+/-5 years) and gender
Exclusion criteria
Exclusion criteria: 1. Acute on Chronic Liver Failure 2. Patients with HBV, HCV, Wilson, Hemochromatosis, alpha 1 antitrypsin deficiency, primary biliary cirrhosis). 3. Patient on amiodarone or tamoxifen or methotrexate. 4. Patient of malignancies other than liver. 5. Patient on chemotherapy 6. HBV related Liver Fibrosis (<= F3).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of the risk factors for liver fibrosis among the first degree relatives of NASH related CirrhosisTimepoint: 0 day | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of the risk factors in patients with NASH related cirrhosis and Hepatitis B Virus Control.Timepoint: 0 day;Assessment of the risk factors in patients with NASH related Cirrhosis and their Healthy Control.Timepoint: 0 day;To assess the Genetic Single Nucleotide Polymorphism in NASH related Cirrhosis patients and their first degree relatives.Timepoint: 0 day;To assess the proportion of Liver fibrosis among first degree relatives of patients with NASH related Cirrhosis.Timepoint: 0 day | — |
Countries
India
Contacts
Public ContactDr Ankit Bhardwaj
Institute of Liver and Biliary Sciences
Outcome results
None listed