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A clinical trial to study the effects of a structured psychological therapy for repetitive negative thinking in patients with depressive and anxiety disorders

Efficacy of Rumination focused Cognitive Behavior Therapy (RFCBT) in patients with depressive and anxiety disorders

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020776
Enrollment
30
Registered
2019-08-19
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F320- Major depressive disorder, singleepisode, mild Health Condition 2: F321- Major depressive disorder, singleepisode, moderate Health Condition 3: F330- Major depressive disorder, recurrent, mild Health Condition 4: F331- Major depressive disorder, recurrent, moderate Health Condition 5: F341- Dysthymic disorder Health Condition 6: F401- Social phobias Health Condition 7: F411- Generalized anxiety disorder

Interventions

Intervention1: Rumination Focused Cognitive Behavior Therapy: Type of cognitive behavior therapy developed by Watkins et al (2007) targeting rumination or repetetive negative thinking through various

Sponsors

Pratishtha Petwal
Lead Sponsor
National Institute of Mental Health and Neurosciences
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Individuals with primary diagnosis of major depressive disorder or dysthymia or generalized anxiety disorder or social anxiety disorder, Educated up to 10th standard, have working knowledge of English or Hindi, and Stabilized on medication for four weeks prior to the entry into the study

Exclusion criteria

Exclusion criteria: 1. History suggestive of head injury, severe neurological/neurosurgical illnesses or general medical illness that could interfere with therapy 2. A primary diagnosis of obsessive-compulsive disorder, schizophrenia or psychosis, schizoaffective disorder, bipolar disorder, current episode of severe depression with psychotic symptoms, current psychoactive substance dependence other than nicotine dependence or clinical evidence of mental retardation 3. Participants who had received structured psychological intervention of more than 8 sessions in the past one year for anxiety or depression

Design outcomes

Primary

MeasureTime frame
Depression and anxiety symptoms as measured on the Depression, Anxiety, Stress Scales (DASS) (Lovibond & Lovibond, 1993)Timepoint: Baseline, post intervention, 1 month follow up and 3 month follow up

Secondary

MeasureTime frame
Repetitive negative thinking, as assessed using the Ruminative Response Scale (RRS; Nolen-Hoeksema & Morrow, 1991) and Penn State Worry Questionnaire (PSWQ; Meyer et al., 1990)Timepoint: Baseline, post intervention, 1 month follow up and 3 month follow up;Severity of clinical symptoms and improvement as measured on Clinical Global Impression Scale (CGI; Guy, 1976)Timepoint: Baseline, post intervention, 1 month follow up and 3 month follow up;Work and social adjustment as measured on the Work and Social Adjustment Scale (WSAS; Mundt, Marks, Greist, & Shear, 2002)Timepoint: Baseline, post intervention, 1 month follow up and 3 month follow up

Countries

India

Contacts

Public ContactPaulomi M Sudhir

National Institute of Mental Health and Neurosciences

paulomi@nimhans.ac.in08026995184

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026