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Combination of laser and light therapy versus laser and blood injection for inducing skin colour in white patches

COMBINATION OF FRACTIONAL CARBON DIOXIDE LASER AND PLATELET RICH PLASMA VERSUS FRACTIONAL CARBON DIOXIDE LASER AND NARROW BAND UV-B TO INDUCE REPIGMENTATION IN THE TREATMENT OF STABLE VITILIGO: A COMPARATIVE STUDY

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020748
Enrollment
50
Registered
2019-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80- Vitiligo

Interventions

Intervention1: FRACTIONAL CARBON DIOXIDE LASER AND PLATELET RICH PLASMA: Patients will receive 4 sessions of fractional co2 laser and prp with 2-week interval. Patients will receive 4 sessions of fr

Sponsors

Vamshi Krishna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with stable vitiligo lesions with less than 15-20% of BSA involvement.

Exclusion criteria

Exclusion criteria: Patients with unstable , universalis and mucosal vitiligo lesions. Patients who have received any topical medications or systemic treatment during the last 2 months before starting the study. Patients who had any contraindications to phototherapy exposure , e.g., history of presence of malignant or pre - malignant skin lesions. Patients with keloids, hypertrophic scars, photosensitivity conditions and koebner phenomenon. Pregnancy and Lactating females. Patients with unrealistic expectation about the result after treatment.

Design outcomes

Primary

MeasureTime frame
Two dermatologists will be asked to record the percentage of improvement (repigmentation) for each patient after completion of the treatment by comparing before and after digital photographs by a 5-point scale. Grade 0 (no repigmentation) Grade 1 (1%-5%) Grade 2 (6%-25%) Grade 3 (26%-50%) Grade 4 (51%-75%) Grade 5 (76%-100%)   Timepoint: 3 months

Secondary

MeasureTime frame
The patients will also be asked at the final visit to rate the overall satisfaction as Visual assessment score(VAS ,0-10) ; 0 level defined as â??Not satisfied at allâ?? while a level of 10 will be defined as â??completely satisfiedâ??. Timepoint: 3 months

Countries

India

Contacts

Public ContactVamshi krishna

Kalinga Institute Of Medical Sciences

kd4639@rediffmail.com9890634707

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026