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COMPARISON OF USING ANTIBIOTICS LIKE AMIKACIN OR METRONIDAZOLE WITH ROUTINELY USED NORMAL SALINE IN LAVAGE OF PERITONEUM IN CASE OF PERFORATION PERITONITIS

METRONIDAZOLE AND/OR AMIKACIN VERSUS NORMAL SALINE PERITONEAL LAVAGE IN PERFORATION PERITONITIS - A RANDOMIZED CONTROLLED STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020745
Enrollment
40
Registered
2019-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K650- Generalized (acute) peritonitis

Interventions

Intervention1: Metronidazole wash: In this group, after doing the definitive surgery for the pathology, the peritoneal cavity will be washed with 4.5L of warm normal saline. Then a mixture of 500 ml n

Sponsors

Department of Surgery Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients of age between 18 and 70 years presenting with perforation peritonitis who will undergo laparotomy.

Exclusion criteria

Exclusion criteria: 1. Diabetes 2. Any other immunocompromised status. 3. Re- exploration within 30 days. 4. Known allergy to metronidazole or amikacin.

Design outcomes

Primary

MeasureTime frame
Patients in all four groups will be compared for 10 days period post laparotomy ans assessed for post operative surgical site infections defined as per CDC criteriaTimepoint: 10 days post laparotomy—

Secondary

MeasureTime frame
Comparison of duration of stay in the hospital in all the four groups as an indicator of morbidity.Timepoint: not applicable—

Countries

India

Contacts

Public ContactPAWAN LAL

Maulana Azaad Medical College

pawanlal@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026