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A clinical study to know the effectiveness of a medicine called magnesium sulphate for epidural anaesthesia in reducing pain during normal delivery

Effectiveness of low dose epidural magnesium sulphate in labour analgesia â?? A randomized control trial.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020679
Enrollment
100
Registered
2019-08-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Epidural bolus of magnesium sulphate with bupivacaine infusion combined with intrathecal fentanyl: Epidural bolus of magnesium sulphate 25mg with bupivacaine 0.1% infusion combined with

Sponsors

Srinivas Institute of Medical Sciences and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Parturients in age group of 18 â?? 35yrs for planned vaginal delivery. 2. Parturients in first stage of labour with cervical dilatation greater than or equal to 3cms. 3. Parturients in height range of 145 â?? 175 cms and in weight range of 50 â?? 100 kgs.

Exclusion criteria

Exclusion criteria: 1.Pregnant patient not consenting for study. 2.History of allergy to local anesthetics. 3.Coagulation abnormality. 4.Infection at the site of the injection. 5.Any abnormality or disease of the spine. 6.Patient with any uncontrolled systemic illness. 7.Parturient with pre-eclampsia and eclampsia who received IV Magnesium for obstetric management. 8.Parturients with cardiac diseases.

Design outcomes

Primary

MeasureTime frame
To assess the effectiveness and quality of labour analgesia with and without epidural bolus dose of 25 mg of magnesium sulphate along with intrathecal fentanyl ( 15 mcg ) and epidural bupivacaine infusion ( 0.1 % ).Timepoint: Patients vitals parameters will be assessed at baseline, 5, 15, 30, 60, 90 and 120 min and labour pain score and fetal well being will be assessed till the delivery

Secondary

MeasureTime frame
Hypotension, motor block, itching, nausea and vomitingTimepoint: At baseline, 5, 15, 30, 60, 90 and 120 min and till the time of delivery

Countries

India

Contacts

Public ContactDr Prashanth Kumar C

Srinivas Institute of Medical Sciences and Research Centre

drprashanthkumarc@gmail.com9738400843

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026