Study to see if discontinuation of oxytocin in active phase of induced labours has an effect on the maternal and fetal outcomes.

: Randomised placebo controlled trial to compare maternal and fetal effects following discontinuation VERSUS continuation of oxytocin in active labour - DOAL study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/08/020657

Enrollment

600

Registered

2019-08-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Discontinuation of oxytocin in active stage of induced labours: In Group 1 patients (Discontinuation/Intervention group), Oxytocin infusion will be discontinued in active stage of labou

Eligibility

Inclusion criteria

Inclusion criteria: All pregnant women with singleton pregnancies undergoing labour induction at term

Exclusion criteria

Exclusion criteria: Multiple pregnancy preterm Previous LSCS Severe pre eclampsia/gestational hypertension abruption meconium stained amniotic fluid

Design outcomes

Primary

Measure	Time frame
Overall LSCS rateTimepoint: AT THE END OF THE PREGNANCY (37-41 WEEKS )	—

Secondary

Measure	Time frame
Maternal: Mean duration of labour, Number of women in Discontinuation group who were restarted back on Oxytocin,Number of women in Continuation group where oxytocin was stopped, Uterine hyperstimulation, Post-partum haemorrhage, Chorioamnionitis, Breast feeding Fetal: Intrapartum CTG abnormalities, APGAR score 7 at 5 mins, NICU admissionTimepoint: AT THE END OF PREGNANCY (37-41 WEEKS)	—

Countries

India

Contacts

Public ContactMANISHA MADHAI BECK

CHRISTIAN MEDICAL COLLEGE , VELLORE

beckmanisha@yahoo.com9787892640

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026