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Comparison of 2 New Locally Acting Medicaments in Periodontal Pockets in Patients with Gum Disorder

Comparative Clinical Evaluation of the Effectiveness of Two Novel Local Drug Delivery Agents Containing Tetracycline HCL micro-particles and Doxycyline Hyclate micro-particles vs Tetracyline HCL fibers (Periodontal AB plus) in Treatment of Periodontal Pockets in Patients with Chronic Periodontitis- A Pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020651
Enrollment
15
Registered
2019-08-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R69- Illness, unspecified

Interventions

Intervention1: tetracycline hcl micro-particles as local drug delivery to be applied once throughout the duration of the study by the Primary Investigator : to be placed in periodontal pockets 1 mon

Sponsors

Dr Nikita Patil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Isolated periodontal pockets >5mm deep. 2) Patients with chronic periodontitis 3) Patient willing to give the informed consent and willing to comply with the study were selected

Exclusion criteria

Exclusion criteria: 1) Allergy or hypersensitivity to tetracycline or related compounds. 2) Use of antibiotics within last 3 months. 3) Patients not maintaining satisfactory oral hygiene after phase1 periodontal therapy. 4) Systemic diseases. 5) Pregnancy. 6) Smoking

Design outcomes

Primary

MeasureTime frame
1. Gingival index (Loe and Silness-1964) 2. Pocket Probing Depth 3. Plaque index 4. Clinical Attachment level Timepoint: baseline, 1 month and 3 months—

Secondary

MeasureTime frame
Gingival index (Loe and Silness-1964)Timepoint: baseline,1 month, 3 months—

Countries

India

Contacts

Public ContactDr Mala Dixit Baburaj

Nair Hospital Dental college

maladixit25@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026