Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: Chewable ascorbic acid tablet: Starting from day 1 of radiotherapy till the end of radiation treatment, patients in this arm will be asked to take the chewable ascorbic acid tablet (500
Sponsors
Burdwan Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Diagnosed with biopsy proven head and neck cancer. 2. Receiving head and neck irradiation or concomitant chemo-radiation for head and neck cancer. 3. Literacy: Standard 4 or higher.
Exclusion criteria
Exclusion criteria: -Any other associated malignancies. -Salivary gland excision during surgery. -Any psychiatric illness. -Patients receiving any other drug that can cause xerostomia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To compare the effect of chewable ascorbic acid tablet and mechanical stimulation on the amount of salivary outflow following head and neck irradiation. 2.To compare the efficacy of chewable ascorbate tablet and mechanical stimulation in reducing the severity of the clinical signs and symptoms of radiation-induced xerostomia. 3.To compare the efficacy of chewable ascorbate tablet and mechanical stimulation in improving quality of life. Timepoint: Day 1, Day 7, Day 14, Day 21 and at the end of radiotherapy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To compare the effect of chewable ascorbic acid tablet and mechanical stimulation on the amount of salivary outflow following head and neck irradiation. 2.To compare the efficacy of chewable ascorbate tablet and mechanical stimulation in reducing the severity of the clinical signs and symptoms of radiation-induced xerostomia. 3.To compare the efficacy of chewable ascorbate tablet and mechanical stimulation in improving quality of life. Timepoint: Day 1, Day 7, Day 14, Day 21 and at the end of radiotherapy | — |
Countries
India
Contacts
Public ContactSamya Dutta
Burdwan Medical College
Outcome results
None listed