Health Condition 1: I39- Endocarditis and heart valve disorders in diseases classified elsewhere Health Condition 2: I361- Nonrheumatic tricuspid (valve) insufficiency Health Condition 3: I52- Other heart disorders in diseasesclassified elsewhere
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18-60 years undergoing elective cardiac surgery of American Society of Anaesthesiologists (ASA) physical status I, II and III
Exclusion criteria
Exclusion criteria: 1. Patient with preexisting history of chronic obstructive pulmonary diseases, acute respiratory distress syndrome, Emphysematous diseases, arrhythmias 2. Patient with documented Pulmonary vein stenosis, any obstruction at right ventricular outflow tract, pulmonary artery, pulmonary vein.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| a.To assess the quantitative effect of positive end expiratory pressure on different levels of baseline central venous pressure. b. To compare the effect of increase in positive end expiratory pressure on change in central venous pressure in patients with or without tricuspid regurgitation.Timepoint: a.The baseline central venous pressure will be noted. The corresponding central venous pressure will be measured following 2 min of application of positive end expiratory pressures at every 15 second for next 1 minute. b.The presence or absence of tricuspid regurgitation will be measured with transesophageal echocardiography before start of procedure. The corresponding central venous pressure will be measured. | — |
Primary
| Measure | Time frame |
|---|---|
| To assess the quantitative effect of positive end expiratory pressure on change in central venous pressure in patients with closed thorax compared to open thorax in patient undergoing cardiac surgery. Timepoint: Three different levels of positive end expiratory pressure (0 cm H2O, 5cm H2O and 10cm H2O) will be applied to the patient before sternotomy and after sternotomy. The central venous pressure will be measured following 2 min of application of positive end expiratory pressure at every 15 second for next 1 minute. The mean value of 4 readings obtained will be calculated and documented. | — |
Countries
India
Contacts
Jawaharlal institute of postgraduate medical education and research