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TO CHECK EFFICIENCY OF LOCAL ANESTHETIC SOLUTION CONTAINING BUPRENORPHINE ADDED TO 2% LIGNOCAINE WITH 1:2,00,000 ADRENALINE INJECTION IN REDUCING PAIN AFTER EXTRACTION AND ALSO THE NUMBER OF PAIN KILLERS CONSUMED BY THE PATIENT .

Efficacy of Buprenorphine added to 2% Lignocaine with 1:2,00,000 Adrenaline in providing postoperative analgesia after extraction of Mandibular Posterior Teeth: A Split Mouth Study.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020631
Enrollment
28
Registered
2019-08-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Modified Local Anesthesia -Lignocaine with Buprenorphine: Addition of buprenorphine in 1:2,0,000 Lignocaine with adrenaline to reduce postoperative pain after extraction of mandibular t

Sponsors

Dr Nimrat Kaur Jawanda
Lead Sponsor
Dr Nimrat Kaur Jawanda
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring bilateral mandibular posterior teeth extractions by transalveolar method including impacted mandibular molars (Pedersons Difficulty Index 3-5) as seen on the preoperative radiograph (OPG). (b) Age Group: 18-40 years without significant medical history or bleeding disorders

Exclusion criteria

Exclusion criteria: Patients in whom the respective nerve block was ineffective (b) Patients with a relevant medical history (c) Patients allergic to the drug used as local anesthetic. (d) Patients who did not follow up regularly (e) Patients who did not return the questionnaire (f) Patients with history of substance abuse or who have consume analgesics 6 hours prior to the procedure done

Design outcomes

Primary

MeasureTime frame
Benefits of buprenorphine added to lignocaine 1:2,00,000 Adrenaline after extraction of mandibular third molars for reducing pain.Timepoint: Benefits will be assesed during the first 72 hours based on the patients pain score and number of analgesics consumed in the first 24 ,48 and 72 hours.

Secondary

MeasureTime frame
Benefits of buprenorphine added to lignocaine 1:2,00,000 Adrenaline after extraction of mandibular third molars for reducing pain.Timepoint: Benefits will be assesed during the first 72 hours based on the patients pain score and number of analgesics consumed in the first 24 ,48 and 72 hours.

Countries

India

Contacts

Public ContactDr Nimrat Kaur Jawanda

Manipal College of Dental Sciences ,Manipal

gadi_mds@rediffmail.com9986455201

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026