Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere
Conditions
Interventions
Intervention1: Combination of ketamine and dexmedetomidine: Patients will receive a loading dose of dexmedetomidine 1 mcg/kg over 10 minutes. This will be followed by injection of ketamine 0.5 mg/kg.
Sponsors
All India Institute of Medical Science New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: a)ASA I & II Patients b)Age 18 - 65 years
Exclusion criteria
Exclusion criteria: a) Refusal of consent. b) Pregnancy. c) Pre-existing cardiac arrhythmias. d) Ischemic heart disease. e) Hypertension. f) Basal heart rate g) Patient on �-blockers. h) Renal or liver insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the difference in the mean SpO2 following administration of ketamine-dexmedetomidine combination as opposed to ketamine-propofol combination for sedation in patients undergoing ERCP.Timepoint: From Induction of IV Sedation to 4hrs After Procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Between the two groups, to determine - The number of times rescue boluses are needed. The changes in heart rate and mean arterial pressure. The number of episodes of significant respiratory depression. The Endoscopistâ??s satisfaction. Time taken to achieve score of 3 on Ramsay sedation scale after stopping infusions. Pain scores following procedure. Time taken to achieve discharge criteria. Timepoint: From Induction of IV Sedation to 4hrs After Procedure | — |
Countries
India
Contacts
Public ContactAjay Singh
All India Institute of Medical Science, New Delhi
Outcome results
None listed