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To compare the pain reliving efficacy of two pain relieving medicines in postsurgery in pain patients coming for lower spine surgeries - due to spinal cord compression

A study comparing the analgesic efficacy of single dose of epidural morphine Vs epidural morphine with ketamine in patients undergoing lumbar laminectomy with or without discectomy - A randomized controlled clinical trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020573
Enrollment
50
Registered
2019-08-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G55- Nerve root and plexus compressionsin diseases classified elsewhere

Interventions

Intervention1: RANDOMIZED CONTROLLED CLINICAL TRAIL: EPIDURAL APPLICATION OF MORPHINE AND KETAMINE Intervention2: randomized controlled clinical trial: comparing epidural morphine and epidural morphin

Sponsors

Institutional Review Board
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I AND II 2. Patients Undergoing Lumbar Laminectomy And Discectomy Surgery 3. Normal Renal Functions

Exclusion criteria

Exclusion criteria: 1. ASA III OR IV 2. BMI >40 3. Impaired Renal Function 4. Intraoperative CSF Leak 5. Any Contraindications to Morphine and Ketamine

Design outcomes

Primary

MeasureTime frame
Time Taken to Receive First Rescue AnalgesiaTimepoint: 3 Hours—

Secondary

MeasureTime frame
1. NRS score 1-10 2. Total Amount of Rescue Analgesic Consumed: Cumulative opioid Consumption 3. Post OP Haemodynamics : HR , BP , RR , sedation 4. Post OP Complications - Vomiting , Pruritis , urinary retention , Respiratory depression Timepoint: 24 Hours—

Countries

India

Contacts

Public ContactPrasadkanna

CHRISTIAN MEDICAL COLLEGE

ramamani@cmcvellore.ac.in8903686991

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026