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Protein quality assessment of commonly consumed foods

Assessment of metabolic availability of limiting amino acids from differently processed milk proteins and standard Indian diets using indicator amino acid oxidation (IAAO) technique in humans

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/08/020568
Enrollment
24
Registered
2019-08-06
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

The Wellcome TrustDBT India Alliance
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. BMI between 18.5 to 25 Kg/m�²

Exclusion criteria

Exclusion criteria: 1. History of smoking or taking other leisure drugs 2. Consumption of alcohol in the previous 24 hours 3. History of antibiotic usage 4 weeks prior to the study 4. On iron supplementation therapy (3 months) 5. On medication such as NSAIDââ?¬•s, proton pump inhibitors or H2 blockers 2 days prior to and on the study day 6. Participation in any nutritional study in the last 6 months 7. History of food allergy, specifically milk, cereal (ragi/rice/wheat), pulse or meat protein 8. Diagnosed with chronic medical or surgical illness

Design outcomes

Primary

MeasureTime frame
Metabolic availability of limiting amino acids from differently processed milk proteins and standard indian diets in healthy human adultsTimepoint: Subjects will be studied once in a week for 8 weeks. On the day of the experiment breath collection will be performed on half hourly fashion in the initial hours and thereafter in 15 mins interval in last 2 hours. Time points of breath collection: Baseline and post meal - 30, 60, 90, 120, 180, 210, 240, 300, 315, 330, 345, 360, 375, 390, 405, 420, 435, 450, 465, 480 minutes

Secondary

MeasureTime frame
To determine true metabolic availability of limiting amino acids from differently processed milk proteins and standard indian diets in healthy human adultsTimepoint: Breath samples will be collected at baseline and post meal 30, 60, 90, 120, 180, 210, 240, 300, 315, 330, 345, 360, 375, 390, 405, 420, 435, 450, 465, 480 minutes

Countries

India

Contacts

Public ContactSulagna Bandyopadhyay

St Johns Research Institute

rebecca@sjri.res.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 25, 2026