Comparative trial of two gels in mild to moderate acne

A randomized, double â?? blind, comparative trial of combined topical adapalene (0.1%) and benzoyl peroxide (2.5%) versus topical benzoyl peroxide (2.5%) monotherapy in grade I and II Acne vulgaris - ABPAV

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/08/020563

Enrollment

Registered

2019-08-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Combined topical adapalene (0.1%) and benzoyl peroxide (2.5%): Drug : Combined topical adapalene (0.1%) and benzoyl peroxide (2.5%) Dose and frequency : once at bedtime application Rou

Eligibility

Inclusion criteria

Inclusion criteria: 1. Untreated male and non-pregnant female above 15 years. 2. Acute, symptomatic Acne vulgaris patients of moderate variety. 3. Those with comedones and papules

Exclusion criteria

Exclusion criteria: 1. Pregnant or nursing females. 2. Patients with Diabetes Mellitus, Malignancy, renal or hepatic dysfunction 3. History of hypersensitivity to any of the study drugs. 4. Patients not willing to comply with protocol requirements. 5. Those who received steroids in last 3 months.

Design outcomes

Primary

Measure	Time frame
Number of lesions ErythemaTimepoint: Week 0 Week 2 Week 4 Week 6	—

Secondary

Measure	Time frame
Quality of lifeTimepoint: Week 0 Week 2 Week 4 Week 6	—

Countries

India

Contacts

Public ContactAnupam Das

Department of Dermatology, KPC Medical College and Hospital

aditichak63@gmail.com9007113980

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026