Comparision of ondansetron and lignocaine for reduction of pain during propofol intravenous injection in adult patient undergoing laparoscopic cholecystectomy.

Comparision of lignocaine and ondansetron for attenuation of propofol induced pain in adult patient undergoing laparoscopic cholecystectomy.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/08/020559

Enrollment

100

Registered

2019-08-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80- Cholelithiasis

Interventions

Control Intervention1: Injection Lignocaine 20% intravenous: administrated 1 minute prior to propofol injection under venous statis at the site of injection of 30-40 mmofHg. Control Intervention2: Inj

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA Grade I and II patients. 2.Patients of either sex, aged 18yrs and above. 3.Patient scheduled for various elective surgical procedures under general anesthesia.

Exclusion criteria

Exclusion criteria: 1.Patients belonging to ASA 3 and 4. 2.Patients with known cardiac disorders, other systemic disorders of lungs and liver. 3.Pregnant patients. 4.Patients for emergency procedures. 5.Patient allergic to propofol, lignocaine or ondansetron. 6.Patient with history of motion sickness, history of PONV, on nasogastric tube and patients with difficult airway.

Design outcomes

Primary

Measure	Time frame
Attenuation of Propofol induced pain by lignocaine and ondansetron in adult patient undergoing laparoscopic cholecystectomy.Timepoint: with in 20 seconds of propofol injection	—

Secondary

Measure	Time frame
Post- operative incidence of nausea and vomiting in two groupsTimepoint: up-till 2 hours post-surgery	—

Countries

India

Contacts

Public ContactAkash Kanojia

PGIMER and Dr R.M.L Hospital

drsoodrajesh@gmail.com9810218916

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026