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To compare and evaluate the efficacy of ozonated olive oil and sodium hypochlorite in killing root canal microorganisms.

Antimicrobial efficacy of commercially available ozonated olive oil and sodium hypochlorite with and without ultrasonic activation in primary endodontic infections- An vivo study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/08/020553
Enrollment
56
Registered
2019-08-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ozonated Olive oil: Ozonated olive oil with and without ultrasonic activation as root canal irrigant Control Intervention1: Sodium hypochlorite: Sodium hypochlorite with and without ult

Sponsors

Garima
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with non-contributory medical history, permanent teeth with necrotic or infected pulp as diagnosed clinically and radiographically with adequate coronal structure for proper isolation, temporization, and restoration will be included.

Exclusion criteria

Exclusion criteria: Patients with systemic conditions, pregnant patients, acute periapical abscess, retreatment cases, patients on antibiotic therapy within three months, teeth with calcified canals, presence of intraoral or extraoral sinus, immature apex, internal and external resorption and periodontal pockets >5mm will be excluded.

Design outcomes

Primary

MeasureTime frame
Microbial coloniesTimepoint: 24 hours of incubation

Secondary

MeasureTime frame
Microbial colonies countTimepoint: after 24 hours

Countries

India

Contacts

Public ContactDr Garima

Sudha rustagi college of dental sciences and research

mttlrksh@yahoo.co.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026