Health Condition 1: K709- Alcoholic liver disease, unspecified
Conditions
Interventions
Intervention1: branched chain amino acids: Branched chain amino acids 1 sachet mixed with water twice daily for 7 days per oral route , along with RIFAXIMIN tablet 400 mg twice daily per oral for 7 da
Sponsors
Pavan kumar KV
Eligibility
Inclusion criteria
Inclusion criteria: 1)patient with hepatic encephalopathy diagnosed according to West Haven criteria. 2)All types of hepatic encephalopathy induced by autoimmune, viral, alcoholic, biliary etiology
Exclusion criteria
Exclusion criteria: 1] presence of a major neuropsychiatric illness, 2] hypersensitivity to RIFAXIMINand BCAA, 3]Presence of inflammatory bowel diseases and intestinal obstruction 4]Serum creatinine levels > twice normal 5]Pregnant and lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1] To determine the effect of BCAA plus RIFAXIMIN in the resolution of hepatic encephalopathy compared with RIFAXIMIN aloneTimepoint: 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1] To determine the effect of RIFAXIMIN plus BCAAon Serum ammonia levels. 2]To determine the effect of RIFAXIMINplus BCAA on duration of hospital stay Timepoint: 7 days | — |
Countries
India
Contacts
Public ContactPavan Kumar KV
pondicherry institute of medical sciences
Outcome results
None listed