Health Condition 1: R609- Edema, unspecified Health Condition 2: R509- Fever, unspecified Health Condition 3: R51- Headache Health Condition 4: R58- Hemorrhage, not elsewhere classified Health Condition 5: R69- Illness, unspecified Health Condition 6: R530- Neoplastic (malignant) related fatigue Health Condition 7: R52- Pain, unspecified Health Condition 8: R561- Post traumatic seizures Health Condition 9: R652- Severe sepsis Health Condition 10: R579- Shock, unspecified Health Condition 11: R55
Conditions
Interventions
Intervention1: na: na
Sponsors
St Johns Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients above 18 years admitted in medical ICU
Exclusion criteria
Exclusion criteria: 1) Age less than 18 years 2) Known severe carotid stenosis ( >50%) or occluded carotid arteries 3) Inadequate transcranial doppler window 4) Pregnant patients 5) Patients with history of Mental retardation 6) Patients not expected to survive for > 24 hours in ICU 7) Cardiac arrythmias at the time of measurement 8) Penetrating trauma to the head or significant ocular trauma 9) Refusal of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Describe the Pulsatility index (PI), Resistivity index (RI), MCA - Peak systolic velocity (Psv), End diastolic velocity (Edv), Mean flow velocity (Mfv), ICP and Cerebral Blood flow index (CBFi) as measured by TCD among patients being admitted in ICUTimepoint: Patients shall be assessed within 24 hours post admission and subsequently every 24 hours till discharge from ICU or death. | — |
Secondary
| Measure | Time frame |
|---|---|
| a)To determine if TCD parameters -PI, RI, Mfv, Psv, Edv, ICP (PI derived) and CBfi (PI derived would improve the predictive ability of severity of illness score such as APACHE II. b)To determine whether the pattern and the distribution of these parameters will help differentiate the pathophysiology of encephalopathy in these patients Timepoint: Patients shall be assessed within 24 hours post admission and subsequently every 24 hours till discharge from ICU or death. | — |
Countries
India
Contacts
Public ContactDr A Thomas Isiah Sudarsan
ST. Johns Medical College Hospital
Outcome results
None listed