Health Condition 1: J00-J99- Diseases of the respiratory system
Conditions
Interventions
None listed
Sponsors
ICMR
Eligibility
Inclusion criteria
Inclusion criteria: 1. Hospital based cohort: Children 6-15 years of age, with history of physician-diagnosed chronic (past 6 months) respiratory diseases (asthma, cystic fibrosis, bronchiectasis and interstitial lung diseases). 2. School based cohort (control group): age 6-15 years, no known history of chronic respiratory diseases. 3. Resident of Delhi and likely to stay in Delhi or willing to come for follow up for next 2 years
Exclusion criteria
Exclusion criteria: 1. Advance disease (patient on life support, on home oxygen or ventilation (invasive or non- invasive)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in spirometry parameters over 2 years of follow-up and their association with ambient air pollutant levels.Timepoint: Every 3 monthly for hospital cohort and every 6 monthly in school cohort | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in following over 2 yearsâ?? period of follow-up: 1.Frequency of respiratory symptoms, frequency of medication use and hospitalisations 2. Airway inflammation 3. Atopy status 4.Oxidative stress biomarkers 5. Peds QoL Timepoint: Frequency of respiratory symptoms, Peds QoL questionnaire will be assessed 3 monthly; biomarkers every 6 monthly for hospital cohort and in addition Peds QoL will be assessed every 6 monthly in school cohort | — |
Countries
India
Contacts
Public ContactDr S K Kabra
AIIMS, New Delhi
Outcome results
None listed