Health Condition 1: L80-L99- Other disorders of the skin and subcutaneous tissue
Conditions
Interventions
Intervention1: platelet rich plasma mesotherapy: prp injected till papillary dermis 1.5 ml at 3-4 sites of melasma on three seatings at interval of 3 months
Control Intervention1: thba2%w/w: applicati
Sponsors
Government medical college bhavnagar
Eligibility
Inclusion criteria
Inclusion criteria: patients with age above 18 years irrespective of their sex clinically diagnosed melasma will be included in study .
Exclusion criteria
Exclusion criteria: Females on oral contraceptive pill Age Pregnant female Tendency for keloid, hypertrophic scar Bleeding disorder Platelet abnormality On anticoagulant drugs Chronic liver disease On oral tretinoin Refusal to allow photographs hiv/hbsag +ve
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified melasma area severity index Physician global assessment scale Patients global assessment scale MelasQOL(melasma quality of life) dermoscopeTimepoint: after 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| dermoscopic and woods lamp dignosis of melasma improvement in masi and melaqol efficasy and safety of boyh modalitiesTimepoint: after 4th week,8th week and 12th week of starting of procedure | — |
Countries
India
Contacts
Public ContactMilan Jhavar
government medical college bhavnagar
Outcome results
None listed