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To compare the efficacy of Open flap debridement, Platelet rich fibrin and Biodentine in the treatment of intrabony defects.

COMPARATIVE EVALUATION OF THE EFFICACY OF OPEN FLAP DEBRIDMENT ALONE AND COMBINATION OF OPEN FLAP DEBRIDMENT WITH BIODENTINE AND PLATELET RICH FIBRIN IN THE TREATMENT OF INTRABONY PERIODONTAL DEFECTS – A RANDOMIZED CLINICAL AND RADIOGRAPHIC STUDY.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020377
Enrollment
80
Registered
2019-07-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Biodentine: Septodent.A calcium silicate based root end filling material. Control Intervention1: Open Flap Debridement.: Debridement, removal of granulation tissue Control Intervention2

Sponsors

Dr Shwetha N
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosis of Periodontitis. (A new classification scheme for periodontal and peri- implant diseases and conditions – introduction and key changes from the 1999 classification).6 2. Subjects aged 25 – 55 years. 3. Subjects with periodontal pockets having probing depth of greater than or equalto 5mm. 4. Subjects having Intrabony defects of greater than of equal to 3mm deep. 5. Good oral hygiene maintainence (PI score 0.1 – 0.9) after etiological periodontal therapy.

Exclusion criteria

Exclusion criteria: 1. Subjects with systemic diseases. 2. Subjects on anticoagulant therapy. 3. Subjects with habit of smoking and alcohol. 4. Subjects with known history of allergy to graft materials. 5. Subjects who have not undergone periodontal surgery within 12 months for the same defects. 6. Pregnant and lactating females. 7. Subjects on antibiotics for past 3 months. 8. Mobility of teeth greater than Grade I.

Design outcomes

Primary

MeasureTime frame
The bone fill changes between test and control groups is set as primary outcomeTimepoint: at 3 and 6 months from baseline.—

Secondary

MeasureTime frame
clinical parameters like Full mouth plaque score, Full mouth bleeding score, Gingival Index, Probing pocket depth and Probing attachment levelsTimepoint: at 3 and 6 months from baseline—

Countries

India

Contacts

Public ContactDr Shwetha N

Government Dental college and research institute, bangalore

mallika948992@gmail.com9880712716

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026