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Assessment of efficacy of neuronavigated theta burst stimulation in obsessive compulsive disorder patient

Efficacy of adjunctive extended neuronavigated theta burst stimulation in patients with obsessive compulsive disorder- a sham controlled study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020366
Enrollment
30
Registered
2019-07-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F422- Mixed obsessional thoughts and acts

Interventions

Intervention1: Extended Theta Burst Stimulation active: 30 sessions of cTBS was administered over the Supplementary motor area at 80 % of MT (motor threshold).cTBS was applied via Magstim Rapid® devi

Sponsors

Central institute of psychiatry
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Diagnosis of Obsessive-Compulsive Disorder using Diagnostic Criteria for Research (DCR) of International Classification of Disease-10th edition (ICD-10, World Health Organization,1992) 2.Age between 18- 60 years of either sex 3.Right handed 4.Patients giving written informed consent

Exclusion criteria

Exclusion criteria: 1.OCD with severe depression as measured by HAM D score > 23 2.Presence of co-morbid neurological or other psychiatric disorder(s). 3.Patient with co morbid substance dependence, except nicotine and caffeine. 4.Patient on any psychotropic medications. 5.Having any metallic implants/parts in body.

Design outcomes

Primary

MeasureTime frame
Primary outcome of the study in change in severity of obsession and compulsion assessed at 0 week and at the end of 3 week of Theta Burst stimulation with the specially designed score sheet.Timepoint: YBOCS, HAM-D, HAM-A, CGI will be applied at the starting of intervention followed by assessment at 3 weeks and finally on follow up at 8 weeks

Secondary

MeasureTime frame
Changes in levels of psychopathology as measured by HAM-D, HAM-A and CGITimepoint: Baseline, 03 weeks and 08 weeks post intervention

Countries

India

Contacts

Public ContactDr Nishant Goyal

Central institute of psychiatry

psynishant@gmail.com9431171162

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026