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Comparing two methods of artificial breathing in terms of post-surgery complications during open abdominal cancer operations

Comparison of lung aeration loss in open abdominal oncologic surgeries after ventilation with Electrical Impedance Tomography guided PEEP versus conventional PEEP â?? a pilot randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020351
Enrollment
40
Registered
2019-07-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C15-C26- Malignant neoplasms of digestive organs Health Condition 2: C51-C58- Malignant neoplasms of female genital organs Health Condition 3: C60-C63- Malignant neoplasms of male genital organs Health Condition 4: C64-C68- Malignant neoplasms of urinary tract

Interventions

Intervention1: Electrical Impedance Tomography guided PEEP: Decremental PEEP titration to be done and optimal PEEP to be identified for each patient. Then mechanical ventilation would be given with th

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective open abdominal oncology surgeries Age 18-65 years, both gender ASA Physical Status I, II and III

Exclusion criteria

Exclusion criteria: Patients who do not give consent for the study Patients with ASA Physical Status IV and above Patients with Body Mass Index (BMI) 35 Patients with moderate to severe derangements in Pulmonary Function Tests Patients with pacemakers Surgeries in which incision does not extend above the level of umbilicus Surgeries lasting less than two hours

Design outcomes

Primary

MeasureTime frame
Modified Lung Ultrasound ScoreTimepoint: Before anaesthesia induction and sixty minutes after extubation

Secondary

MeasureTime frame
HaemodynamicsTimepoint: Preoperative baseline, after induction, after intubation, after 1st recruitment, after PEEP titration, after 2nd recruitment, at start of surgery, every 30 minutes until extubation, after extubation;PaO2/FiO2 ratiosTimepoint: Before surgery, after second recruitment manoeuvre, one hour after randomization, after surgery before extubation, one hour after extubation and 24 hours after extubation;Postoperative pulmonary complicationsTimepoint: From extubation until 3 days postoperatively

Countries

India

Contacts

Public ContactDr Karthik AR

AIIMS New Delhi

vkchanpadia@gmail.com9013172162

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026