Health Condition 1: L80- Vitiligo
Conditions
Interventions
Intervention1: Topical Clobetasol with oral hydroxychloroquine: once daily 0.05% topical clobetasol for 2weeks with 1week gap as a cyclical process plus oral hydroxychloroquine 200mg once daily
Contro
Sponsors
Bankura Sammilani Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >=18 yrs to 2.Extension of preexisting vitiligo lesion with in last one year. 3.Appearance of new lesion with in last one year. 4.Presence of Koëbner phenomenon during the past 1 year 5.Trichrome or quadrichrome vitiligo 6.No use of any systemic therapy for 4 weeks prior to enrollment in the study; 7.Informed consent obtained 8.Willing for twice weekly treatment with narrow band ultraviolet B phototherapy.
Exclusion criteria
Exclusion criteria: 1.Childhood vitiligo. 2.Pregnant and lactating women. 3.Patient taking known photosensitizer drugs or immunosuppressive therapy. 4.Concomitant immune defects, heart disease, renal failure, malignancy. 5.Patient having retinopathy. 6.Neurological or psychiatric disorders. 7.History of photosensitivity or photo mediated disorder. 8.Participation in any clinical trial within the last 3 months 9.Substance or alcohol abuse. 10.Patient having diabetes mellitus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effectiveness of topical clobetasol with oral hydroxychloroquine versus topical clobetasol with narrow band ultraviolet B (NBUVB) phototherapyTimepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the improvement in quality of life with the above mentioned regimeTimepoint: 6 months;To assess the tolerability and safety of the above mentioned regimeTimepoint: 6 months;To estimate the difference in cost incurred for the above mentioned regimeTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactDrDhiman Tarafdar
Bankura Sammilani Medical College and Hospital
Outcome results
None listed