Effect of root canal treatment on inflammatory marker levels in blood in adults with root end infection-clinical study

Influence of Endodontic treatment on (hsCRP) C-reactive Protein levels in adults with apical lesions of endodontic origin- A Prospective , longitudinal interventional trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/07/020302

Enrollment

Registered

2019-07-22

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: Root canal treatment: Preoperative hsCRP evaluation before root canal treatment and 2 months and 6 months post operative hsCRP evaluation Control Intervention1: NIL: NIL

Eligibility

Inclusion criteria

Inclusion criteria: MILD-MODERATE PERIODONTITIS 18-45 years PERIAPICAL LESION > 3MM RADIOGRAPHICALY

Exclusion criteria

Exclusion criteria: AGE > 45 Yrs smokers systemic disease(Diabetes mellitus, Hypertension) patients taken antibiotic treatment 3 months back pregnancy BMI > 30 kg/m2

Design outcomes

Primary

Measure	Time frame
Evaluation of hsCRP before and after root canal treatment in patients with periapical lesionTimepoint: preoperative postoperative 2 months postoperative 6 months	—

Secondary

Measure	Time frame
Radiographic evaluation of apical lesions of endodontic originTimepoint: preoperative postoperative 2 months postoperative 6 months	—

Countries

India

Contacts

Public ContactLingeswaran poornima

Dr.MGR Educational research institute university

arpradeep@vsnl.com9840135711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026