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Effective dose of phenylephrine infusion for preventing hypotension in elective caesaerean deliveries.

To estimate the effective dose of phenylephrine infusion for preventing spinal anaesthesia induced hypotension in elective caesarean deliveries, a randomized control trial.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020231
Enrollment
364
Registered
2019-07-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Phenylephrine i.v. infusion @ 25 mcg/ml/min: dose: 25mcg/ml/min of phenylephrine infusion given by i.v. route is started in group A patients soon after spinal anesthesia is given and b

Sponsors

DEVDUTTA RAIGURU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: >37 weeks gestation, ASA grade 2 females posted for elective caesarean delivery.

Exclusion criteria

Exclusion criteria: 1. American Society of Anaesthesiologists (ASA) grade III and IV pregnant females. 2. Unwilling patients. 3. Patients with any uncontrolled systemic disorder like diabetes, hypertension, pre-eclampsia, HELLP syndrome, hepatic or renal impairment, severe airway disorder, seizure disorder or eclampsia, any cardiac diseases. 4. Patients with known hypersensitivity or allergy to either Phenylephrine. 5. Patients with any contraindication for undergoing spinal anaesthesia.

Design outcomes

Primary

MeasureTime frame
prevention of hypotension following spinal anaesthesiaTimepoint: blood pressure & heart rate recorded before spinal anaesthesia then every one min after spinal anaesthesia until baby is delivered then every 3 mins until end of surgery

Secondary

MeasureTime frame
to prevent hypoxia of babyTimepoint: APGAR score at birth then after 1 min and 5 mins and 10 mins.

Countries

India

Contacts

Public ContactDevdutta Raiguru

KALINGA INSTITUTE OF MEDICAL SCIENCES

dr.pradip.maharana@gmail.com8895440004

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026