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Comparison of paraffin versus ceramide based moisturizers in atopic dermatitis

Evaluation of a paraffin based moisturizer as compared to a ceramide based moisturizer in children with atopic dermatitis: A double blinded, two group equivalence randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020200
Enrollment
70
Registered
2019-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L209- Atopic dermatitis, unspecified

Interventions

Intervention1: Paraffin: Paraffin based moisturizer, twice daily application all over body for 6 months Control Intervention1: Ceramide: Ceramide based moisturizer, twice daily application all over bo

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Children <18 years of age with mild to moderate AD (SCORAD 15-40)

Exclusion criteria

Exclusion criteria: a) Children with severe systemic illness b) Children receiving systemic immunosuppression therapy in last 1 month c) Children unable to come for follow up

Design outcomes

Primary

MeasureTime frame
Difference in SCORAD in children with mild to moderate AD receiving paraffin based moisturizer compared to ceramide based moisturizer used twice daily at 3 monthsTimepoint: 3 months

Secondary

MeasureTime frame
1. Time to remission and disease-free duration in children with mild to moderate AD receiving paraffin based moisturizer compared to ceramide based moisturizer used twice daily at 6 months Timepoint: 6 months;3. Quantity of topical corticosteroid required in children with mild to moderate AD receiving paraffin based moisturizer compared to ceramide based moisturizer used twice daily at 6 monthsTimepoint: 6 months; 2. Improvement in TEWL values in children with mild to moderate AD receiving paraffin based moisturizer compared to ceramide based moisturizer used twice daily at 6 months as measured by DERMALAB, cortex technologiesTimepoint: 6 months

Countries

India

Contacts

Public ContactSachin Gupta

All India Institute of Medical Sciences

drntbhari@gmail.com01126594985

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026